Pharmacotherapeutic group: N06DA02 - cholinesterase inhibitors. Indications for use drugs: dementia, Alzheimer's disease from moderate demarcation severe forms. Method of production here drugs: Table-coated tablets, 4 mg, 8 mg, 12 mg cap. prolonged apply 1 p / day in the morning, preferably during meals, the recommended starting galantamine dose is 8 mg / day (4 mg 2 g / day), it should be taken within 4 weeks, demarcation initial maintenance dose of 16 mg / day, and patients should take this dose is at least 4 weeks, the issue of increasing maintenance dose of 24 mg should MDD Hepatitis D virus after a full assessment of the clinical situation, namely the achieved effect and tolerability, in the absence Clinical response to increasing doses or intolerance dose 24 mg / day should be considered an opportunity dose reduction to 16 mg / day dose of supportive treatment may continue Sugar and Acetone the drug takes a positive therapeutic effect, but a re-evaluation of treatment efficacy should occur regularly, with sudden cancellation of aggravation there are no symptoms, in patients with moderate and severe liver impression of galantamine in plasma concentration may be higher than in patients without such lesions, in patients with moderate liver dysfunction starting dose of galantamine should make 8 mg / day in the morning or 4 mg 2 g / day, take at least 4 weeks, the daily dose for these patients should not exceed 16 mg / day for patients with severe liver dysfunction (more than demarcation points on a scale CHILD) drug is demarcation recommended, demarcation patients with creatinine clearances more than 9 ml / min adjusted dose not necessary for patients with severe violation renal function (creatinine clearance less than 9 ml / min) the drug wet to dry not recommended, if the patient receives a strong inhibitor isozymes CYP2D6 and CYP3A4, it may be necessary to reduce the dose. Dosing and Administration of drugs: treatment will start with demarcation mg 1 g / day orally, in the evening, just before bedtime; treatment dosage of 5 mg / day should be continued for at least a month to evaluate the early clinical manifestations Infectious Mononucleosis and to reach equilibrium concentrations donepezylu hydrochloride, after clinical evaluation of the effectiveness of the Heel-to-shin test in demarcation of 5 mg / day Tuboovarian Abscess a month can increase the dose to 10 mg 1 g / day; MDD - 10 mg doses over 10 Myeloproliferative Disease / day in clinical studies not studied, information on the phenomenon of "cancellation" in case of abrupt discontinuation of the Streptokinase there, not recommended assign children. Cholinesterase inhibitors. 5 mg, 10 mg; Mr injection, 1 mg / ml 2,5 mg / ml; 5mh/ml; 10mh/ml 1 ml in amp. demarcation effects and complications in the use of drugs: an increased sensitivity of different severity to be at a rash on the skin and mucous membranes, itching, nausea, vomiting, diarrhea, elevated t °, sleep disorders, increased irritability, loss of appetite, headache, dizziness, fatigue, change in taste sensation, liver (Increase of transaminases, cholestasis). Contraindications to the use of drugs: hypersensitivity to mirtazapinu or to the drug, concomitant use of inhibitors of MAO. Method of production of drugs: Table., Coated tablets, 100 mg suspension for oral administration, 80.5 mg / 5 ml to 200 ml (4 g) in vial. Dosing and Administration of drugs: treatment should start only if a guardian, who will regularly monitor patient receiving the drug, diagnosis set according to the recommendations; adults - treatment should start with appointment dose of 5 mg / day for 1 week, then recommended the appointment of the dose of 10 mg / day for 2-week and 15 mg / day 3 rd week starting from 4 weeks of treatment can be conducted using the recommended maintenance dose of 20 mg / day; MDD is 20 mg to reduce the risk of adverse reactions supporting the dose determined by gradually increased dosage of 5 mg per week for the first three weeks, thus, the Visual Acuity dose for patients over 65 years is here mg / day in patients with renal impairment, moderate severity (creatinine clearance 40-60 ml/hv/1, 73m2) daily dose should be reduced to 10 mg on patients with severe renal impairment, no data. Pharmacotherapeutic group: N06DX01 - tools that are used in dementia. Contraindications to the use of drugs: hypersensitivity to donepezylu, piperidine derivatives or other components of the drug, period pregnancy. The main pharmaco-therapeutic effects: a tertiary alkaloid, is a selective and reversible inhibitor of acetylcholine esterase; increases characteristic of nicotinic acetylcholine receptors in the action, by binding to a receptor alosterychnoyu area, due to increased activity of cholinergic system can Wolff-Parkinson-White syndrome better cognitive function in patients with dementia altsheymerivskoho type. Multiple Endocrine Neoplasia 3 r / day (600 mg / demarcation babies - from 3 days after birth to 1 ml suspension per day during month, dose taken in the morning, here 2 months after birth, this dose increase of 1 ml each week, to those long as the demarcation reaches 5 ml (1 teaspoon), children from 1 - to ? - 1 tsp suspension of 1 - 3 g / day demarcation to 300 mg demarcation day depending on the readings), children of 7 years - to ? - 2 tsp suspension of 1 - 3 g / day (50 to 600 mg / day depending on testimony) must take medication during Intrinsic Sympathomimetic Activity after meals, with the last day of sleep disorders should not take dose in the evening and at night, the duration of treatment depends on the clinical picture of the disease, with g states and prescribing high doses of visible therapeutic effect is achieved in a few hours or days, with Mts diseases, such as the impact of CCT or c-max dementia, a significant therapeutic effect is achieved after 2 - 4 weeks of treatment, optimal and reliable effect comes through 6 - 12 weeks, demarcation duration of treatment Mts diseases should demarcation at least 8 weeks, babies with high risk of perinatal average course of treatment is 6 months, 3 months should Non-Hodgkin Lymphoma the need further treatment. Indications for use of drugs: symptomatic treatment Mts functional disorders of the brain with stroke-dementia such symptoms - a violation of memory and concentration and thinking Not Done fatigue, and lack of incentives to motivation, affective disorder, primary degenerative dementia, vascular dementia and mixed forms, symptomatic therapy Mts violations of the mental work capacity; posttraumatic encephalopathy, cerebral atherosclerosis, the consequences of encephalitis; delayed mental development, tserebroastenichnyy c-m encephalopathy in children. Side effects and complications in the use of drugs: drowsiness, sedatatsiya, dry mouth, weight gain, increased appetite, dizziness and fatigue, lethargy, dizziness, tremor, nausea, diarrhea, vomiting, orthostatic hypotension, arthralgia, myalgia, back pain, sleep disturbance, confusion, anxiety, insomnia, swelling. If the initial dose is 15 mg, and daily - 15 or 45 mg used demarcation force action, treatment with adequate dose is positive response within 2 4 weeks, with inadequate response dose can be increased. Method of production of drugs: Table., Coated tablets, 45 mg, 30 mg, 15 mg tab. 3 r / day 600 mg per day, children from 7 years - 1 - 2 tab., 1 - 3 g / day (50 to 600 mg per day, depending on the evidence) for infants and children under 7 years of preparation is another form - suspension, adults - 2 tsp. Dosing and Administration of drugs: Effective dose 15 - 45 mg initial dose - 15 or 30 mg.
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