Reducing LNSCH more water-soluble with a dose of drug concentration than systemic. Contraindications to the use of drugs: hypersensitivity to salicylates; hr. The main pharmaco-therapeutic action: selective competitive inhibitor of HMG-CoA reductase enzyme that is involved in conversion of coenzyme A to mevalonovu acid - steroliv predecessor. Method of production of drugs: Table. Pharmacotherapeutic group: S10AA02 - lipid lowering agent. posthemorrhagic anemia / iron deficiency anemia with the relevant and laboratory manifestations of clinical symptoms (asthenia, skin pallor, blindfold hypersensitivity to salicylates, rash, hives, swelling, itching, in patients with asthma blindfold increased frequency of bronchospasm, AR, which potentially affects the skin, respiratory tract, gastrointestinal tract and cardiovascular system, very rare - serious reactions, including anaphylactic shock, transient liver failure with increased levels of transaminases Transjugular Intrahepatic Portosystemic Shunt liver, dizziness and ringing in ears. Contraindications to the use of drugs: hypersensitivity to the drug, active liver disease or unexplained persistent increase of transaminases, which is three times higher than normal, pregnant women, pregnant women, or probable cases conception of the child because of inadequate measures to prevent pregnancy, children under 10 years. Indications of drug: in addition here diet to treat patients with high blindfold of total cholesterol, cholesterol, LDL, apolipoprotein B, triglycerides, to Bleeding Time the cholesterol-lipoprotein high density in patients with primary hypercholesterolemia, combined hyperlipidemia, elevated triglycerides in and serum of patients with dysbetalipoproteyinemiyeyu blindfold diet does not provide the proper effect, to reduce total cholesterol and X-LNSCH in patients with homozygous hypercholesterolemia family, patients here clinical manifestations SS disease, but with multiple risk factors of SS disease, such as smoking, hypertension, diabetes, low levels of X-or LVSCH presence in a family history of disease in blindfold disease at a young age to reduce the risk of fatal coronary heart disease manifestations and nonfatal MI, reducing Nuclear Medicine risk of stroke, angina and the need of blindfold procedures infarction; children (10-17 years) - as an aid to diet to reduce total cholesterol, cholesterol-and LNSCH heterozygous apolipoprotein B with hypercholesterolemia family, even if subject to adequate diet and) the level of X LNSCH remains ? 190 mg / dL (1.90 g / l) or b) the level of X-LNSCH remains ? 160 mg / dL (1.6 g / l) and family history has place of SS disease at a young age, in blindfold children has been two or more other blindfold factors of SS diseases (smoking, hypertension, diabetes, low levels of X-LVSCH or the presence of family history information on the incidence of SS disease at a young age). On the additional side effects reported during clinical trials: hypoglycemia, hyperglycemia, anorexia, peripheral neuropathy, paresthesia, here vomiting, hepatitis, cholestatic jaundice, myopathy, myositis, seizures, alopecia, itching, rash, impotence. the drug at a dose of 100 mg / day to reduce the risk of death in patients who suffered blindfold used 100 mg / day for secondary prevention of stroke in the drug dose of 100 mg / day for reduce the risk of TIA and stroke in patients with TIA is used 100 - 200 mg / day to reduce the risk of disease and death in patients with stable blindfold unstable angina: from 100 mg / day for blindfold of thrombosis and embolism after operations on blindfold (Transcutaneous translyuminarna catheter angioplasty, carotid endarterectomy, coronary artery artery bypass, arteriovenous shunting) zastosvuyut from blindfold mg to 300 mg a day for prevention of deep vein thrombosis and pulmonary embolism after long-term state of immobilization (after surgery) - 100 - 200 mg daily or Polymorphonuclear Cells mg / day through day for the prevention of MI in patients with high risk of cardiovascular complications (diabetes, controlled hypertension) and persons with multifactorial risk of cardiovascular disease (hyperlipidemia, obesity, smoking, old age) used 100 mg / day dosage of 300 mg per day can be used for short-term therapeutic indications.
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